Category: Evidence Explainers
Plain-English guides to study quality, statistics, evidence hierarchies and scientific uncertainty.
FDA Warning on Unapproved GLP-1 Products and “Research Use Only” Marketing
The FDA’s September 2026 GLP-1 warning explains why unapproved, counterfeit and falsely labelled products cannot be treated as equivalents of approved medicines.
Read analysis →Phase 1, 2, 3 and 4 Trials: What Each Stage Can—and Cannot—Establish
Clinical-trial phases answer different questions. Learn why Phase 1 safety, Phase 2 signals, Phase 3 confirmation and Phase 4 monitoring should not be collapsed.
Read analysis →How to Read a Clinical Trial Registry Record Without Overclaiming
A field-by-field guide to study status, design, outcomes, estimands, dates, enrolment and results on ClinicalTrials.gov and ANZCTR.
Read analysis →ARTG, Unapproved Therapeutic Goods and Clinical Trials: An Australian Reader’s Guide
How to distinguish ARTG inclusion, clinical-trial access, exemptions, overseas approval and online ‘research use only’ claims in Australia.
Read analysis →From Lyophilised Peptide to Solution: Stability Variables and Study Design
A non-procedural guide to the factors that determine peptide stability after dissolution, including formulation, temperature, light, oxidation, adsorption, agitation and study design.
Read analysis →BPC-157 and TB-500 Together: Why “Synergy” Claims Exceed the Evidence
A critical appraisal of combination claims: complementary mechanisms are a hypothesis, not proof of improved outcomes, safety, stability or compatibility.
Read analysis →Retatrutide Mechanism: What Triple GIP, GLP-1 and Glucagon Agonism Means
A receptor-by-receptor explanation of retatrutide, separating established human observations from preclinical mechanisms and popular oversimplifications.
Read analysis →How to Read a Peptide Certificate of Analysis: A Field-by-Field Guide
An Australia-focused guide to verifying a peptide certificate of analysis, spotting red flags and separating identity, HPLC area, assay, sterility and regulatory status.
Read analysis →Independent Batch Testing: Sampling, Chain of Custody and Reproducibility
Why an independent result is only as strong as the sample it represents, the custody record that connects it to a lot, and the method’s reproducibility.
Read analysis →Research Peptide Storage Records: Temperature Excursions, Light and Traceability
A quality-system guide to documenting storage conditions and assessing temperature excursions without relying on generic peptide storage claims.
Read analysis →